Pacemaker

INTRODUCTION

Pacemakers are electronic devices that stimulate the heart with electrical impulses to maintain or restore a normal heartbeat. This topic review will discuss pacemakers, when they may be necessary or appropriate, the types of pacemakers that are available, and the precautions patients need to take after having a pacemaker placed.

THE HEART’S CONDUCTION SYSTEM AND “NATURAL PACEMAKER”

The heart has its own built-in electrical system, called the conduction system. The conduction system sends electrical signals throughout the heart that determine the timing of the heartbeat and cause the heart to beat in a coordinated, rhythmic pattern. The conduction system stimulates precise contractions of the heart’s chambers to ensure that blood is pumped effectively.

The electrical signals, or impulses, of the heart are generated by specialized tissue called the sinoatrial (SA) or sinus node. The sinus node is sometimes called the heart’s “natural pacemaker.” Each time the sinus node generates a new electrical impulse; that impulse spreads out through the heart’s upper chambers, called the right atrium and the left atrium. This electrical impulse stimulates the atria to contract, pumping blood into the lower chambers of the heart (the right and left ventricles).

The electrical impulse then spreads to another area of specialized tissue located between the atria and the ventricles, the atrioventricular (AV) node. The AV node momentarily slows down the spread of the electrical impulse, to allow the left and right atria to finish contracting.

From the AV node, the impulse spreads into a system of specialized fibers called the bundle of His and the right and left bundle branches. These fibers distribute the electrical impulse rapidly to all areas of the right and left ventricles, stimulating them to contract in a coordinated way. With this contraction, blood is pumped from the right ventricle to the lungs, and from the left ventricle throughout the body.

ARRHYTHMIAS

The heart’s conduction system must function normally for the heart to beat properly and to pump blood effectively to meet the body’s needs. Problems with the flow of electrical impulses in the heart can cause heart rhythm disturbances known as “arrhythmias.” This general term indicates an abnormality in the pattern of electrical activation of the heart.

Bradyarrhythmias — Bradyarrhythmias are heart rhythm abnormalities that cause the heart to beat too slow. Most bradyarrhythmias are due to one of two kinds of problems: sinus bradycardia or heart block.

Sinus bradycardia occurs when the heartbeat is too slow because the heart’s “natural pacemaker” in the top right chamber (the right atrium) is operating too slowly. Although some people (for example, competitive athletes) may have a slow heartbeat as a result of good health, in others sinus bradycardia is an abnormal condition that may require treatment.

Heart block is a term for a delay or interruption in the heart’s electrical wiring (the conduction system), causing the electrical impulses to travel too slowly or to be stopped. There are several kinds of heart block, classified according to location (where in the conduction system the block occurs) and degree (whether the block is mild, causing delayed conduction, or severe, causing conduction to stop).

ARRHYTHMIA SYMPTOMS 

The symptoms of arrhythmias vary, depending upon the specific arrhythmia and other factors, especially if there is underlying heart disease. While some people may have no symptoms, others may have various symptoms and signs. Symptoms may include:

The decision to treat an arrhythmia with a pacemaker (or any other treatment) depends in part upon whether the person has symptoms or not as well as the severity of the symptoms. In some cases, the heart rate is simply too slow, and a pacemaker is needed to effectively pump the blood out of the heart.

Underlying causes — A variety of conditions can lead to the development of cardiac arrhythmias. Some of the more common causes include:

TEMPORARY AND PERMANENT PACEMAKERS

Artificial pacemakers are electronic devices that stimulate the heart with electrical impulses to maintain or restore a normal rhythm in people with slow heart rhythms. There are many situations in which an artificial pacemaker may be recommended.

Most commonly, a pacemaker is used for a slow heart rate (bradyarrhythmia) as described above. The decision to use such a device, as well as which specific type, will depend upon multiple factors, including:

How they work — An artificial pacemaker provides an electrical impulse (or “discharge”) that can stimulate the heart, thus restoring or maintaining a regular heartbeat. Although various types of artificial pacemaker devices are available, they generally include the following components:

TYPES OF PACEMAKERS

 A variety of types of pacemakers and modes of pacing have been developed to restore or sustain a regular heartbeat in different ways. All contemporary pacemakers sense the intrinsic activity and stimulate the heart only when the intrinsic heart rate falls below the programmed pacing rate. Essentially all contemporary pacemakers also incorporate rate responsive capability. This depends on a “sensor” incorporated into the pacemaker that can sense activity or respiratory rate and can alter the heart rate based on the perceived physiologic need.

Pacemakers may also be single, dual, or triple chambered:

IMPLANTATION 

The pacemaker is most commonly implanted into soft tissue beneath the skin in an area below the clavicle, which is known as prepectoral implantation. this is located under the skin and fat tissue but above the pectoral muscle. The pacemaker leads are typically inserted into a major vein (transvenously) and advanced until the leads are secured within the proper region(s) of heart muscle. The other ends of the leads are attached to the pulse generator.

Less commonly, the pulse generator is placed under the skin of the upper abdomen.

Generally, the pacemaker is implanted in a sterile laboratory or operating room by a specialist (cardiologist, surgeon, or cardiac electrophysiologist) with experience in this procedure. Local anesthesia and often conscious sedation are used to make the procedure as pain-free as possible. General anesthesia is rarely required. The position of the pacemaker leads is usually checked using X-ray imaging (called fluoroscopy). The length of the procedure depends upon the type of device being placed.

Leadless pacemakers are generally implanted through a leg vein and placed directly in the heart muscle without the need for a separate pulse generator.

Recovery from the procedure is rapid, but there may be some restrictions on arm movement and activities for the first two to four weeks. Lead dislodgement is more common in the first few weeks after implantation. The hospital stay is usually brief, and the procedure can be performed as an outpatient. Uncommon but possible risks associated with permanent pacemaker implantation include collapsed lung (pneumothorax), infection, perforation/tamponade, and bleeding.

Once implanted, pacemakers can be programmed to change the baseline heart rate, the upper heart rate at which the pacemaker will pace, and heart rate changes that should occur with exercise.

FOLLOW-UP CARE 

People who have a permanent pacemaker will require periodic surveillance of the implanted device. The status of the pacemaker will be regularly checked or “interrogated” (often done remotely using a telephone or a secure web-based system) to provide information regarding the type of heart rhythm, the functioning of the pacemaker leads, the frequency of utilization of the pacemaker, the battery life, and the presence of any abnormal heart rhythms.

All contemporary devices are programmable with information and settings that can be altered and stored. Information is obtained by transmitting data from the pulse generator to a programmer, usually done during a follow-up office visit. However, with newer pulse generators it may be possible to obtain information about the pacemaker’s performance by downloading data from the patient’s device to the internet and then to the caregiver’s office. In older devices, pacemaker status can be checked routinely via the telephone using a trans-telephonic device.

The pulse generators are usually powered by lithium batteries that function for an average of five to eight years before they need to be replaced. When the batteries start to wear out, they do so in a very slow and predictable fashion, allowing sufficient time to be detected and pulse-generator replacement planned. Replacing the pulse generator usually requires a simple procedure in which a skin incision is made over the old incision, the old generator is removed, and a new generator is implanted and joined with the existing leads, assuming the existing leads are functioning normally.

The pacemaker leads are usually used indefinitely, unless a specific problem occurs (eg, the lead loses contact with the heart, the lead breaks, or the lead is not functioning properly). In such circumstances, the lead may require replacement. Often, the old lead is left in place but disconnected from the pulse generator and capped, and a new lead is inserted. Removal of an old lead is feasible but difficult in most cases, because of the formation of scar tissue binding the lead to the blood vessels and heart muscle. Lead removal is usually necessary if the system becomes infected.

AVOIDING ELECTROMAGNETIC INTERFERENCE

Although contemporary pacemakers are less susceptible to interference than older models, electromagnetic energy can interfere in some cases. Thus, experts advise that people with pacemakers be aware of the following:

Household appliances — Pacemaker manufacturers do not recommend any special precautions when using normally functioning common household appliances such as microwave ovens, televisions, radios, toasters, and electric blankets.

Cellular phones — People with a pacemaker or a defibrillator should know that items with strong magnetic fields (eg, cellular phones with magnets for wireless charging [iPhone 12], magnetic accessories such as certain “smart watches”) can affect the function of the device if they are very close (less than six inches) to their device. Cell phones without strong magnets are unlikely to cause problems with pacemakers or defibrillators.

If you have a pacemaker or a defibrillator, the safest strategy is to use your cell phone at the ear on the side opposite the cardiac device. When you are carrying your phone, keep it in a pocket or bag below your waist. If you’re not sure whether your phone or watch is likely to cause problems with your cardiac device, check with the manufacturer or your doctor.

Anti-theft systems — Electromagnetic anti-theft security systems are often found in or near the workplace, at airports, in stores, at courthouses, or in other high-security areas. Although interference with a pacemaker is possible, it is unlikely that any clinically significant interference would occur with the transient exposure associated with walking through such a field. Based upon several studies and observations, experts advise that patients with pacemakers should:

Metal detectors at airports — Similar to antitheft systems, metal detectors at airports can potentially interfere with pacemakers, although this is unlikely. Such exposure has been shown to cause interference in some cases and may be related to the duration of exposure and/or distance between the security system and the pacemaker. Metal detectors will likely be triggered by the presence of a pacemaker and therefore at places such as airports, it will be important for individuals with pacemakers to carry an identification card for their pacemaker, and airport personnel will likely prefer to do a manual search.

External electrical equipment — External electrical fields do not seem to cause a problem for most people with a pacemaker. However, in workplaces that contain welding equipment or strong motor-generator systems, because interference can inhibit pacing, it is recommended that a person with an implanted cardiac device remain at least two feet from external electrical equipment, verify that the equipment is properly grounded, and leave the immediate locale if lightheadedness or other symptoms develop.

Diagnostic or therapeutic procedures — Certain types of surgery and procedures may interfere with pacemakers. Most importantly, the use of electrocautery can inhibit pacemaker function. It is not uncommon therefore that a pulse generator may require specific reprogramming before the procedure and programming back to its baseline condition after the procedure. In some instances, a magnet is all that is required on the device to make sure that there is no problem with the device during the procedure. Such procedures include:

Thus, doctors, dentists, and other health care providers should be informed about a person’s pacemaker. If a procedure associated with pacemaker interference is contemplated, the possible benefits, risks, and alternatives should be considered and discussed, as appropriate. People with pacemakers should carry a medical identification card for emergencies.